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Topamax weight loss dosing chart – PDR Search

If that works I may cut the phentermine out completely as a test to see if I can sleep better.

William Murphy
Monday, August 16, 2021
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  • Measurement of baseline and periodic serum bicarbonate is recommended during topiramate therapy.

  • Just started 50mg at bedtime and 25mg in morning. I have been taking topamax 50mg for about a week now and have gain 20lbs which put me at obese I seen my dr.

  • Patients who develop unexplained symptoms of hyperammonemia encephalopathy while receiving antiepileptic therapy should discontinue the afflicting drug and receive prompt treatment for hyperammonemia.

  • Michelle J February 20,pm. Topiramate Dosage Medically reviewed by Drugs.

  • GK was the psychiatrist in charge for the patients reported in this study. Subscribe to our newsletters.

Frequently asked questions

Although this interaction has not been studied, predictions can be made based on metabolic pathways. Several studies have investigated the use of topiramate in bipolar disorders. Imatinib: Moderate Imatinib is a potent inhibitors of cytochrome P 2C9 and might decrease topiramate metabolism leading to increased topiramate serum concentrations and a risk of adverse reactions. Sufentanil: Moderate Because the dose of the sufentanil sublingual tablets cannot be titrated, consider an alternate opiate if topiramate must be administered. Loperamide is metabolized by the hepatic enzyme CYP3A4; topiramate is a mild inducer of this enzyme.

The clinical significance is unknown; however, results of routine blood glucose monitoring should be carefully followed during coadministration of pioglitazone and topiramate to ensure adequate glucose control. Do not save for later topmax. Desipramine: Moderate Tricyclic antidepressants, when used concomitantly with anticonvulsants, can increase CNS depression and may also lower the seizure threshold. Bupropion: Moderate Bupropion should not be used by patients with a preexisting seizure disorder because it may lower the seizure threshold. Therefore, concurrent use of flibanserin and CYP3A4 inducers, such as topiramate is not recommended. Sprinkle capsules: Swallow whole. Nortriptyline: Moderate Tricyclic antidepressants, when used concomitantly with anticonvulsants, can increase CNS depression and may also lower the seizure threshold.

I topamax weight loss dosing chart it varies from person to weigyt which side effects you get, everyone wants the weight loss but unfortunately you may end up with something far less desirable. Qsymia is the combination of Phentermine and Topamax in one pill Maybe, but before you use it there are some things you need to know. I just started Topamax for insomnia and it works great.

Background

Any information will be helpful. I have been on Topiramate Topamax mg and Phentermine 30mg and sometimes I just don't drive now. View all 9 comments.

One patient N 10 complained of paraesthesia, sore tongue and bad taste in her mouth dosing chart stopped topiramate during an earlier treatment on Figure 1 this coincides with an earlier short period of weight loss. Moderate Carbonic anhydrase inhibitors such as acetazolamide cause a decrease in serum bicarbonate and may induce non-anion gap, hyperchloremic metabolic acidosis. Anticonvulsants should be prescribed in the smallest quantity consistent with good patient management in order to reduce the risk of overdose. Flurbiprofen: Moderate Concurrent use of topiramate and drugs that affect platelet function such as NSAIDs may increase the risk of bleeding. Monitoring of drug concentrations if therapeutic monitoring is advised for the anticonvulsant is recommended. Imatinib: Moderate Imatinib is a potent inhibitors of cytochrome P 2C9 and might decrease topiramate metabolism leading to increased topiramate serum concentrations and a risk of adverse reactions.

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We do not perform regular formal ratings of the mood of our patients. Moderate Close clinical monitoring is advised when administering topiramate with rilpivirine due to the potential for rilpivirine treatment failure. Ritonavir is metabolized by this enzyme. In a pooled analysis of placebo-controlled trials, bleeding was more frequently reported in patients receiving topiramate compared to placebo. Felbamate: Moderate Concurrent use of topiramate and drugs that cause thrombocytopenia such as the anticonvulsant felbamate may increase the risk of bleeding.

A retrospective and prospective review of 41 children mean age: 6. Do not break, crush, or chew it. Am Ropamax Psychiatry. Decreased isavuconazonium concentrations may lead to a reduction of antifungal efficacy and the potential for treatment failure. Swallow the food mixture right away without chewing. Hydrochlorothiazide, HCTZ; Metoprolol: Moderate Concurrent use or topiramate, a carbonic anhydrase inhibitor, with non-potassium sparing diuretics e. Taking these drugs together may decrease velpatasvir plasma concentrations, potentially resulting in loss of antiviral efficacy.

Regulating refers to matching your appetite to the number of calories that you consume. However I have been trying to lose weight which includes eating good meals and exercising. Extended-Release: -Partial onset seizures: topamax weight loss dosing chart mg orally once a day -Primary generalized tonic-clonic seizures: mg orally once a day The dose should be achieved by titration: Initiate therapy at 25 to 50 mg orally once a day followed by titration in increments of 25 to 50 mg every week to an effective dose. I started to not even care if I was losing weight because all I wanted to do was sleep. Anyone else have this trouble? If more than 1 dose has been missed, patients should be instructed to contact their healthcare provider -Extended-release: If missed, take a soon as possible, do not double the next dose. Lisa January 22,am.

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It should be speculated that dose in relationship to bodyweight as well as tolerance may also play a topamax weight loss dosing chart. In general, the more areas that your weight loss medication "attacks" the better and long lasting your results will be. Lessen Saliva Production — Topamax has the ability to reduce the production of saliva and thereby it results in the poorer taste. Even if your brother or sister used Topamax for weight loss and it worked doesn't mean it will work for you.

Free E-newsletter Subscribe to Housecall Our general interest e-newsletter keeps you up to date on a wide variety of health topics. In contrast, almost all of the above open cchart used topiramate as an add-on therapy. Hydroxychloroquine can lower the seizure threshold; therefore, the activity of antiepileptic drugs may be impaired with concomitant use. Patients and caregivers should be informed of the increased risk of suicidal thoughts and behaviors and should be advised to immediately report the emergence or worsening of depression, the emergence of suicidal thoughts or behavior, thoughts of self-harm, or other unusual changes in mood or behavior.

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Topamax weight loss dosing chart with some researches and studies, it is proved that this Topiramate helps to lose topwmax weight and make you stay fit and slim. Monthly Newsletter. Daily MedNews. I'll be so tired by 7pm, and go to bed at 10ish and Im still up wide awake 2am. The dose should be achieved by titration according to the following schedule Table 1 : Table 1: Monotherapy Titration Schedule for Adults and Pediatric Patients 10 years and older Morning Dose Evening Dose Week 1 25 mg 25 mg Week 2 50 mg 50 mg Week 3 75 mg 75 mg Week 4 mg mg Week 5 mg mg Week 6 mg mg.

Nikki July 14,am. Like others I felt depressed. Conclusion Topamax is a medication which can potentially help with weight loss. Those that consistently take between mg and mg of Topamax daily, have reported that weight loss is virtually effortless. I go about my day as normal. Let's face it: Not all weight loss therapies work for all people. When saliva is reduced, it can result in poorer taste and people may lose some of their normal appetite — leading to weight loss.

What is Topamax?

Alternatively, the discontinuation of HCTZ therapy may require a dose increase in topiramate. Safety Clinical trials and experience with topiramate have not identified serious safety concerns. Dichlorphenamide: Moderate Use dichlorphenamide and topiramate, another carbonic anhydrase inhibitor, together with caution as both drugs can cause metabolic acidosis.

Despite the side effects reported in this and loss dosing chart studies, topiramate is generally well tolerated. Article PubMed Google Scholar. Phenothiazines: Moderate The phenothiazines, when used concomitantly with anticonvulsants, can lower the seizure threshold. Ethinyl Estradiol; Norethindrone: Moderate Topiramate may increase the clearance and compromise the efficacy of progestins used in contraception or hormone replacement therapies. Rights and permissions Reprints and Permissions. Nemeroff CB: Safety of available agents used to treat bipolar disorder: Focus on weight gain. Isavuconazole, the active moiety of isavuconazonium, is a sensitive substrate of this enzyme.

However, this is considered to be a class effect. Ibuprofen: Moderate Concurrent use of topiramate and drugs that affect platelet function such as NSAIDs may increase the risk of dosing chart. Chlorothiazide: Moderate Topiramate is a carbonic anhydrase inhibitor. Use caution when topiramate is prescribed with agents known to predispose patients to similar heat-related disorders such as trospium. Follow your doctor's orders or the directions on the label. After some of the first patients complained of paraesthesia and headaches, we routinely started making the increases only at 2-weekly intervals. The dosage should be halved for patients with renal impairment i.

More about Qsymia (phentermine / topiramate)

I'm personally of the belief that, even though dosing chart may work, there are better options available for weight loss. Since many overweight people are addicted to food, Topamax may remove this addictive urge. Good luck, consult with docs, take care, congratulations on trying your best to help yourselves, you are brave and sound like great people.

In addition, patients receiving hemodialysis may need dose adjustments chxrt relation to their dialysis sessions see Dosage. Isavuconazonium: Moderate Caution and close monitoring are warranted when isavuconazonium is administered with topiramate as there is a potential for decreased concentrations of isavuconazonium. Ticagrelor: Moderate Concurrent use of topiramate and drugs that affect platelet function such as aspirin, ASA and other salicylates or platelet inhibitors may increase the risk of bleeding. Full size image. This medicine comes with a Medication Guide. Weight changes in the patients described in the study.

That amounted to 3 dress sizes and 4 bra band sizes. Dosing chart plasma level monitoring is not required to optimize therapy. What are the effects of alcohol on this medication? Immediate-Release: to mg orally daily in 2 divided doses -Initiate with 25 to 50 mg orally once a day; increase in increments of 25 to 50 mg per week to an effective dose. Did it work for you?

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Search Search. Some find this amusing, some frustrating, but fortunately, it does not last loxs. Topiramate or Topamax is generally an anticonvulsant medicine that widely used to treat epileptic seizures, migraine headache, anxiety, bipolar disorders, borderline personality disorder and nerve pain. Find out everything you need to know about weight loss drugs in our prescription weight loss pill guide.

  • Sprinkle capsules: Swallow whole. Moderate Concurrent administration of topiramate with dasabuvir; ombitasvir; paritaprevir; ritonavir or ombitasvir; paritaprevir; ritonavir may result in decreased concentrations of dasabuvir, paritaprevir, and ritonavir.

  • Obesity, it seems, is turning out to be a much more complex disease than was once thought. I'm not sure what to do now.

  • Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine: Moderate Monitor for reduced efficacy of hydrocodone and signs of opioid withdrawal if coadministration with topiramate is necessary; consider increasing the dose of hydrocodone as needed.

  • Chlorothiazide: Moderate Topiramate is a carbonic anhydrase inhibitor. Bisoprolol; Hydrochlorothiazide, HCTZ: Moderate Concurrent use or topiramate, a carbonic anhydrase inhibitor, with non-potassium sparing diuretics e.

In most cases, signs and symptoms abate with discontinuation of either topiramate or valproate. Topiramate is an inducer of CYP3A4, while perampanel is a substrate of this enzyme. After administration, fosaprepitant is rapidly converted to aprepitant and shares the same drug interactions. He did not like its effect and stopped treatment after one month. The weight-gain caused by many psychotropic drugs is a major cause for poor compliance with such medications and could also increase cardio-vascular morbidity among psychiatric patients.

Dolutegravir is partially metabolized by this isoenzyme. Sign up for the free AFP email table of topaamx. Induction of CYP3A4 by topiramate may significantly reduce the plasma concentrations of simeprevir, resulting in treatment failure. Tirofiban: Moderate Concurrent use of topiramate and drugs that affect platelet function such as aspirin, ASA and other salicylates or platelet inhibitors may increase the risk of bleeding.

Usual Adult Dose for Epilepsy

Mesoridazine: Charrt Topamax weight loss dosing chart phenothiazines, when used concomitantly with anticonvulsants, can lower the seizure threshold. For patients requiring use of such drugs, an alternative to linagliptin is strongly recommended. Doxepin: Moderate Tricyclic antidepressants, when used concomitantly with anticonvulsants, can increase CNS depression and may also lower the seizure threshold. Other measures in conjunction with discontinuation of topiramate may be helpful. Topiramate is contraindicated for use in any patient hypersensitive to the drug or any of the product components.

  • Arch Neurol. Drug information provided by: IBM Micromedex.

  • Topamax may help to keep the number of calories that you burn "steady" by boosting your metabolism.

  • Topiramate was prescribed as part of our routine clinical practice, as an add-on medication, or as a replacement of a mood stabilizer. Jallon P, Picard F: Body weight gain and anticonvulsants: a comparative review.

  • Ive been taking Topamax for 2 months now, and see my Dr. However I have been trying to lose weight which includes eating good meals and exercising.

  • This suggests that topiramate may undergo renal tubular reabsorption.

Ethinyl Estradiol; Etonogestrel: Moderate Topiramate may increase the clearance and compromise the efficacy of progestins used in contraception or hormone replacement therapies. According to the Canadian Network for Mood and Anxiety Treatments CANMAT guidelines, there is level 3 evidence for use of topiramate as a third-line adjunct agent in the maintenance treatment of bipolar disorder; however, topiramate is not recommended as monotherapy for acute mania and is not recommended as monotherapy in the maintenance treatment of bipolar disorder. Free E-newsletter Subscribe to Housecall Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Consider the benefits and risks of topiramate in women of childbearing potential, particularly when it is being considered for conditions not usually associated with permanent injury or death.

Or do u think its too early? Because these medications almost always result in the weight being regained once chqrt appetite returns to normal making them largely ineffective! Email address. I hike each morning at least 3 miles or at least get a walk in with a group of ladies that are on the journey to be healthy with me.

Dichlorphenamide: Moderate Use dichlorphenamide and topiramate, another carbonic anhydrase inhibitor, together with caution as both drugs can cause metabolic acidosis. Rivaroxaban: Moderate Concurrent use of topiramate and anticoagulants may increase the risk of bleeding. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Increased weight, high levels of smoking and reduced exercise are likely to be the main factors leading to such an increased mortality. Want to use this article elsewhere?

How Does Topiramate cause Weight Loss?

I want to go back on it since I am trying to quit grains and sugar all together. Topamax may help to keep the number of calories that you burn "steady" by boosting your metabolism. Do you know any other successful ways of using this topamax for weight loss?

I take melatonin, sleeping pills, seroquel, clonidine, Vistaril even xanax! But the main thing you should remember is the dosage, time span, lifestyle habits, intake of other medications and genetics will play a major role other than taking this drug for weight loss. I actually went to the doctor thinking I had a bad kidney infection. While this may sound silly, this drug can have potent effects on memory, lead some people to feel dizzy, and result in profound disorientation.

I also happen to formulate the best supplements on the market well, at least in my opinion! Topamax did not control appetite for me but it took away my sugar and carb cravings. I had a hysterectomy before taking Topamax so I cannot say how those side effects are, but it does make me forget words in the middle of a conversation. It may also reduce overexcited nerves within this region. If more than 1 dose has been missed, patients should be instructed to contact their healthcare provider -Extended-release: If missed, take a soon as possible, do not double the next dose.

Topiramate-treated patients showed improvement in drug use problems and employment problems as measured by Addiction Severity Index ASI composite scores. Monitor the treated patient for drug efficacy and side effects. Darunavir; Cobicistat: Moderate Caution is warranted when cobicistat is administered with topiramate as there is a potential for decreased concentrations of cobicistat. Amphetamines: Major Concurrent use of amphetamines and urinary alkalinizers, such as topiramate, should be avoided. Additionally, concurrent use of topiramate and anticoagulants may increase the risk of bleeding. Dronedarone is metabolized by CYP3A. Ivabradine: Major Avoid coadministration of ivabradine and topiramate.

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If you were specifically struggling with weight, they may prescribe Qsymia, which contains Topamax as part of its formulation. I take mgs in the am and mgs. I'm personally of the belief that, even though they may work, there are better options available for weight loss.

  • There were 12 patients who were judged responders after 5 weeks, and they had a mean weight loss of 4.

  • This refers to the number of calories that your body burns on a daily basis and is closely correlated with your metabolism.

  • This condition is reversible with cessation of either valproic acid or topiramate.

  • But the main thing you should remember is the dosage, time span, lifestyle habits, intake of other medications and genetics will play a major role other than taking this drug for weight loss. Why do you think you started losing again 6 months ago?

In four cases an anticonvulsant was exchanged with topiramate, in the remaining cases topiramate was given as an add-on loss dosing chart. Drug Safety. Response rate was In addition, seizures have been reported during the use of molindone, which is of particular significance in patients with a seizure disorder receiving anticonvulsants. Methenamine; Sodium Acid Phosphate: Moderate Carbonic anhydrase inhibiting drugs, such as topiramate a weak carbonic anhydrase inhibitor can alkalinize the urine, thereby decreasing the effectiveness of methenamine by inhibiting the conversion of methenamine to formaldehyde. Do not chew or crush. Sofosbuvir; Velpatasvir: Major Use caution when administering velpatasvir with topiramate.

Those odsing have been on the drug for an extensive period may notice that weight loss stops once tolerance is developed. Or do u think its too early? Certain people may experience considerable weight loss from this drug, while others may remain weight neutral or even experience weight gain. Topamax Topiramate is an anticonvulsant medication that is primarily used for the treatment of epilepsy, but has also been approved for migraine prevention and as an adjunct to phentermine for weight loss. For this reason, you generally want to avoid medications which focus solely on appetite reduction as a means of weight loss.

82 Answers

Use of topwmax drugs together may decrease the plasma concentrations of grazoprevir and could result dosing chart decreased virologic response. Monitor for changes in moods or behaviors, or for other CNS effects. Perphenazine; Amitriptyline: Moderate The phenothiazines, when used concomitantly with anticonvulsants, can lower the seizure threshold. Perphenazine: Moderate The phenothiazines, when used concomitantly with anticonvulsants, can lower the seizure threshold.

  • Sertraline: Moderate Concurrent use of topiramate and drugs that affect platelet function such as selective serotonin reuptake inhibitors SSRIs like topiramate may increase the risk of bleeding.

  • Phentermine - This medication is an appetite suppressant and also may help boost metabolism. Also I do get full really fast and only eat one or two meals a day.

  • At the endpoint they showed 0.

  • I'm now at my ideal weight and struggle to eat.

  • But with some researches and studies, it is proved that this Topiramate helps to lose your weight and make you stay fit and slim.

  • Topamax may help to keep the number of calories that you burn "steady" by boosting your metabolism. To escalate the dose: Increase to Qsymia

These medications do NOT work very well long-term and almost always result in weight gain after you stop taking them. It worked for me! I think that the nightly larger dose made a difference. Your cart is empty Return to Shop. But make sure to follow the directions that are prescribed on the label either by asking your doctor or pharmacist to get detailed information.

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PubMed Google Topamax weight loss dosing chart. Dapsone: Minor The metabolism of dapsone may be accelerated when administered concurrently with topiramate, a known wsight of CYP3A4. These two patients had refused to take other mood-stabilizing drugs for fear of weight gain and only agreed to take topiramate as monotherapy, having heard that it will not cause weight gain. CAS Google Scholar. Measure sodium bicarbonate concentrations at baseline and periodically during dichlorphenamide treatment.

Follow your doctor's orders or the directions on the chart. The level of statistical significance for weight loss at each time-point during the follow-up, olss to baseline, was determined with a paired-samples t-test. Sign up now. Diphenhydramine; Phenylephrine: Major Although not specifically studied, coadministration of CNS depressant drugs with topiramate may potentiate CNS depression such as dizziness or cognitive adverse reactions, or other centrally mediated effects of these agents. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below.

I have been taking topamax 50mg for about a week now and have gain 20lbs which put me at obese I seen my dr. I am on 50 mg for cgart first week and going up to mg in my second. Extended-Release: -Partial onset seizures: to mg orally once a day -Primary generalized tonic-clonic seizures: mg orally once a day The dose should be achieved by titration: Initiate therapy at 25 to 50 mg orally once a day followed by titration in increments of 25 to 50 mg every week to an effective dose. On 25mg. Like others I felt depressed. I'm Westin Childs D.

More about Topamax (topiramate)

Some speculate topakax dosages above mg may result in more drastic weight loss. Email address. I don't know I got so messed up from risperidone deight didn't even know that I don't want anyone to ever get over looked again just keep your eyes and ears topamax weight loss dosing chart good luck to you!!! I want to lose weight so bad and nobody would prescribe anything or help me everyone over looked the fact that even my husband told them I honestly charged everything diet exercise everything for a yr and nothing and that was the second time so for bi polar two of my friends I noticed who don't know each other had been losing tons of weight both for this both for different mental reasons I take medication and maybe it was kinda wrong but I was trying different things anyways and hadn't found one so I thought a medication that would help lose weight and help with my mental stuff too sounds good right

Addiction Controller — Topiramate targets the addiction centers of the brain by changing the neural pathways that work within the addiction control centers of the brain and also reduces the overexcited nerves within the region. Topamax may help to keep the number of calories that you burn "steady" by boosting your metabolism. Side Effects of Topamax While the above may sound like a dream come true for people desperate to lose weight, Topamax is a powerful drug, and weight loss may come at a price. Now I'm 14 pounds from my ideal weight and where my rheumatologist wants me. Drinking a lot of water helps with fogginess in the morning. Those that are taking the medication for the purpose of treating a condition like Bipolar disorder may not like the weight loss.

  • This content does not have an English version.

  • I was curious about the effects of Topamax after my psychiatrist put me on it today 50mg.

  • Dichlorphenamide: Moderate Use dichlorphenamide and topiramate, another carbonic anhydrase inhibitor, together with caution as both drugs can cause metabolic acidosis. The day of treatment is on the x-axis.

  • Yes I was on the medicine for bout 2 yrs and at first I was eating good and real healthy then all a sudden I started dropping weight and I went to the doctor and she was like that medicine is a weight lost it was 75 pounds that I dropped I hate it cause I eat so much but not gaining any weight back I want to put it back on I dot like to be the size that I am.

  • The weight loss was great, the brain fog was terrible!

Patients and caregivers should be informed of the increased risk of suicidal thoughts and behaviors and should be advised to immediately report the emergence or worsening of depression, the emergence of suicidal thoughts or behavior, thoughts of self-harm, dosing chart other doskng changes in mood or behavior. Choose a single article, issue, or full-access subscription. According to the Canadian Network for Mood and Anxiety Treatments CANMAT guidelines, there is level 3 evidence for use of topiramate as a third-line adjunct agent in the maintenance treatment of bipolar disorder; however, topiramate is not recommended as monotherapy for acute mania and is not recommended as monotherapy in the maintenance treatment of bipolar disorder. Topiramate can cause fetal harm when administered to a pregnant woman. Ask your doctor if you have any questions.

Several studies have investigated the use of topiramate weitht bipolar disorders. The increased topamax weight loss dosing chart in this population is due to a number of factors, including life-style and diet, but a major cause is the side effect profile of the medications that are prescribed long-term for their illness. He did not like its effect and stopped treatment after one month. Third, topiramate inhibits excitatory transmission by antagonizing some types of glutamate receptors.

What is Topamax (Topiramate)?

You are not using the right dose - This usually isn't a problem but it's worth considering. I went on this site to deight if I wanted to try it again but it looks like it still has the " brain dead" side effect. Burning more calories in your muscles skeletal muscles may also be a way to improve metabolism and caloric burn day in and day out. This dose can be increased up to 15mg of Phentermine and 92mg of Topiramate.

Serum medication concentrations when available may assist in identifying toxicity. In those with serious events, risk factors for bleeding were often present, or patients were taking other drugs that cause thrombocytopenia or affect platelet function or coagulation. Get Permissions. Topiramate is excreted in human breast milk.

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If use together is necessary, obtain fosing ECG prior to lacosamide initiation and after treatment has been titrated to steady-state. Inducers of CYP3A4 may decrease the concentration of doxorubicin and compromise the efficacy of chemotherapy. If these agents are used in combination, the patient should be carefully monitored for a decrease in brexpiprazole efficacy. Cross-sensitivity between antibiotic sulfonamides and nonantibiotic sulfonamides, such as topiramate, is controversial. Dipyridamole: Moderate Concurrent use of topiramate and drugs that affect platelet function such as aspirin, ASA and other salicylates or platelet inhibitors may increase the risk of bleeding. Use caution when combining atovaquone; proguanil with CYP2C19 inhibitors, such as topiramate. Emtricitabine; Rilpivirine; Tenofovir disoproxil fumarate: Moderate Close clinical monitoring is advised when administering topiramate with rilpivirine due to the potential for rilpivirine treatment failure.

Pemoline: Moderate A reduction in seizure threshold has been reported following concomitant administration of pemoline with anticonvulsant agents. Ezogabine: Moderate Concurrent use of topiramate and drugs that cause thrombocytopenia such as the anticonvulsant ezogabine, may increase the risk of bleeding. In addition, seizures have been reported during the use of molindone, which is of particular significance in patients with a seizure disorder receiving anticonvulsants. When an anticonvulsant is being used to manage behavior, stabilize mood, or treat a psychiatric disorder, the facility should attempt periodic tapering of the medication or provide documentation of medical necessity as outlined in the OBRA guidelines.

Further information

Topiramate is a relatively new antiepileptic drug. Tirofiban: Moderate Concurrent use of topiramate and drugs that affect platelet function such as aspirin, ASA and other salicylates or platelet inhibitors may increase the risk of bleeding. Taking these drugs together may decrease velpatasvir plasma concentrations, potentially resulting in loss of antiviral efficacy. Methods Topiramate was prescribed as part of our routine clinical practice, as an add-on medication, or as a replacement of a mood stabilizer. Clinicians should be aware that cognitive and neuropsychiatric events are among the most common adverse reactions seen with topiramate use.

Levonorgestrel: Moderate Topiramate aeight increase the clearance and compromise the efficacy of progestins used in contraception or hormone replacement therapies. This could be a major problem with compliance and is one of the main reasons for discontinuation of treatment [ 110 ]. Tramadol: Moderate Topiramate may contribute to the CNS depression seen with tramadol; tramadol may also decrease the seizure threshold in some patients and thus, potentially, interfere with the ability of anticonvulsants to control seizures. When used in combination, the plasma concentrations of boceprevir may decrease. The tablet may taste bitter if it is held in the mouth or chewed.

I took Topamax about 12 years ago. I am a 46 years old, female. Disorientation : Those that take Topamax may feel so disoriented as a result of their treatment, that they may have a difficult time functioning and remembering to actually eat. In other words, since you will be on multiple medications that can cause weight loss, the amount of weight you lose will be more significant than if you were just taking Topamax as a standalone treatment. That's what I'm using them for what mg are u using.

How to use Topiramate for Weight Loss:

Zonisamide: Moderate Monitor for evidence of metabolic acidosis, kidney stones, heat intolerance, decreased sweating dosing chart increased body temperature and bleeding if coadministration of topiramate and zonisamide is necessary. Ethinyl Estradiol; Topsmax Ferrous fumarate: Moderate Topiramate may increase the clearance and compromise the efficacy of progestins used in contraception or hormone replacement therapies. Consider the benefits and risks of topiramate in women of childbearing potential, particularly when it is being considered for conditions not usually associated with permanent injury or death. Sulindac: Moderate Concurrent use of topiramate and drugs that affect platelet function such as NSAIDs may increase the risk of bleeding.

  • Diphenhydramine: Major Although not specifically studied, coadministration of CNS depressant drugs with topiramate may potentiate CNS depression such as dizziness or cognitive adverse reactions, or other centrally mediated effects of these agents.

  • It should also be mentioned that if you are on stimulant-related medications such as Adderall or Wellbutrin, you may end up experiencing a synergistic weight loss effect. Hey I am taking topamax for start of 3rd WK now.

  • This content does not have an Arabic version. Assessment of blood ammonia levels may be advisable in patients presenting with symptoms of hypothermia.

  • Meloxicam: Moderate Concurrent use of topiramate and drugs that affect platelet function such as NSAIDs may increase the risk of bleeding. Increased body weight is also a major health hazard.

This also applies to combination products containing topiramate, such as phentermine; topiramate. Its effectiveness appears to be similar to that of other antiepileptic drugs and beta blockers. Glyburide: Minor Coadministration of glyburide with topiramate may decrease systemic exposure to glyburide. Etonogestrel: Moderate Topiramate may increase the clearance and compromise the efficacy of progestins used in contraception or hormone replacement therapies.

In view of that, we did not expect any clear improvements in the mood or course of illness of this patient population. Mestranol; Norethindrone: Moderate Topiramate may increase the clearance and compromise the efficacy of progestins used in contraception or hormone replacement therapies. Initially, 50 mg per day PO administered in 2 divided doses. Concurrent use of cariprazine with CYP3A4 inducers, such as topiramate, has not been evaluated and is not recommended because the net effect on active drug and metabolites is unclear.

He revised critically ddosing paper and contributed towards the analysis and discussion. Additional information Competing interests G. Several studies, including this one, show that topiramate has a strong potential to induce weight loss which is sustained for at least one year. Loperamide; Simethicone: Moderate The plasma concentration and efficacy of loperamide may be reduced when administered concurrently with topiramate.

You are not using the right dose - This usually isn't a problem but it's worth considering. Angela August 15,pm. I accept the Terms and Privacy Policy. Despite the drug being effective in reducing the prevalence of seizures, its mechanism of action that produces therapeutic effects is unknown.

I an exstreamly tired, having a hard time pronouncing certain certain words, remembering things and a weight gain. Because this wejght was originally designed to treat seizures epilepsy it works primarily by acting on the brain. Regulation of hormones 4 - Other medications focus on "balancing" fat storing hormones such as leptin, insulin or thyroid hormones. Reply Link. I go fishing,kayaking,camping,motorcycles,atvs,snowmobiles, painting, adult coloring. That amounted to 3 dress sizes and 4 bra band sizes.

Frequently asked questions

According to the British National Formulary guidelines [ 37 ], an anti-obesity drug should be considered only for those with a BMI of 30 or greater pageand we felt that this recommendation should be followed in the case of Topiramate, even if this drug is not licenced for this use. Its effectiveness appears to be similar to that of other antiepileptic drugs and beta blockers. Women of childbearing age who are not planning a pregnancy should use effective contraception because of the fetal risks of oral clefts and being small for gestational age. Alternatively, the discontinuation of HCTZ therapy may require a dose increase in topiramate. Several studies have investigated the use of topiramate in bipolar disorders.

Pioglitazone: Moderate A decrease in the exposures of pioglitazone and its active topamax weight loss dosing chart were observed in a clinical trial during concurrent use of topiramate. Limited data available. Benzoic Acid; Hyoscyamine; Odsing Methylene Blue; Phenyl Salicylate: Moderate Carbonic anhydrase inhibiting drugs, such as topiramate a weak carbonic anhydrase inhibitor can alkalinize the urine, thereby decreasing the effectiveness of methenamine by inhibiting the conversion of methenamine to formaldehyde. Doravirine; Lamivudine; Tenofovir disoproxil fumarate: Minor Concurrent administration of doravirine and topiramate may result in decreased doravirine exposure, resulting in potential loss of virologic control.

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Yes I was on the medicine for bout 2 yrs and at first I was eating good and real healthy then all a sudden I started dropping weight and I went to the doctor and she was weighg that medicine is a weight lost it was 75 pounds that I dropped I hate it cause I eat so much but not gaining any weight back I want to put it back on I dot like to be the size that I am. That said, it is estimated that weight loss is among the most common side effects of the drug Topamax. Michelle J February 20,pm. So, people having pressure inducing substances will no longer do so and thereby stay healthy. This side-effect comes from a few different properties of the medication. Angela August 15,pm. I take mg a day.

Extended-Release: -Partial onset seizures: to mg orally once a day -Primary generalized tonic-clonic seizures: mg orally once a day The dose should be achieved by titration: Initiate therapy at 25 to 50 mg orally once a day followed by titration in increments of 25 to 50 mg every week to an effective dose. I took topamax mg at night for nerve pain in from a back injury. Why do you think you started losing again 6 months ago? Side Effects While Topamax may be effective for weight loss it doesn't come without cost.

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