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Npr microbes obesity: Immigrating To The U.S.? Get Ready For A New Gut Microbiome (And Maybe More Pounds)

They found that in less than 24 hours the gut's microbial populations changed abruptly, according to a study in the journal Science Translational Medicine. Microbiologist Ronald Evans of the Salk Institute in California, who wrote an article accompanying the studies, agrees.

William Murphy
Tuesday, June 19, 2018
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  • Heard on All Things Considered.

  • His team took two groups of mice -- one lean and one obese -- and transplanted microbial communities from their gut into the intestinal tracts of mice that were previously germ-free.

  • Hes chair of the department of microbiology and molecular genetics at Harvard Medical School.

Your turn. So his team took completely germ free mice and basically fed them human gut bacteria. Half of them got bacteria taken from skinny mice.

  • Enlarge this image.

  • By using twins, the researchers were trying to eliminate any genetic variation that could influence the results. In an article accompanying the report, Alan Walker and Julian Parkhill of the Wellcome Trust Sanger Institute in Britain called the findings an "intriguing" step toward finding ways to fight obesity, including developing "relatively simple mixtures of bacteria for testing as anti-obesity therapeutics.

  • NPR transcripts are created on a rush deadline by Verb8tm, Inc. But unlike a lot of American comfort foods, he says, "I know it's good for me.

  • We're going to npr microbes obesity a break and when we come back we're going to talk lots more about, well, a search for life on earth by looking at Mars. By probiotic you're referring to a different type of probiotic, not the type of probiotics that are present in fermented milk products that everybody is most familiar with.

  • Heard on Fresh Air. An immune suppression system in the blood of newborn babies could be key to building a healthy microbiome.

The Argentine makes more frequent visits to the restroom. The rest are from bacteria, viruses and other microorganisms. What do they do? Experiments in microbees and a look at the weight of more than 11, British babies point in the same direction. He points to the trillions of microbes that live in our gut, doing everything from encoding enzymes to serving as pathways for vitamin production to digesting the parts of food we can't digest on our own. Others prefer the desert-dry skin of the forearm.

Heard on Fresh Air. The patient was treated with a transfusion of gut microbials npr microbes obesity a healthy individual's fecal material to restore the bacterial flora in the intestinal tract -- and symptoms improved. Your Health. One researcher said parents would be better off spending their money on good food for their kids instead of probiotics. NPR Shop. And, finally, the researchers showed that the animals were unable to be colonized by the lean microbes when they were fed diets aimed at simulating a typical unhealthful Western diet high in saturated fats and low in fiber.

But as soon as we pass out of the birth canal, when we are fetched by a doctor's hands, placed in a hospital crib, put on our mother's breast, when we drag a thumb across a blanket and stick that thumb in our mouths, when we swallow our first soft food, we are invaded by all sorts of bacteria. Clostridium difficile causes severe diarrhea and can frequently return, even when treated with antibiotics. It's busy down there: a gut bacterium splits into two, becoming two new cells. Scientists have discovered new clues about how microbes in our digestive systems may affect health. Enlarge this image. Rob Stein.

European researchers found that the less diverse those microbes are, the more likely people are microbess gain weight, become obese and develop risk factors for serious health problems. The researchers then transplanted those microbes into the guts of lab mice who didn't have any of their own microbes. In fact, they may well be the reason you're healthy.

Npr microbes obesity work is just the beginning of what Gordon hopes will be a whole obesityy of experiments to tease out how diet and microbes interact to affect nutrition and weight gain. Heard on All Things Considered. Bacterial Bonanza: Microbes Keep Us Alive There are 10 times more microbial cells on and in our bodies than there are human cells. Also, special thanks to the "bacteria" recruited for the radio skit: NPR's Margot Adler, Jim Zarroli, Agnes Janiszewski and -- especially because of his extraordinary ability to scream with delight -- Josh Rogosin. Next, the scientists let the animals live together. September 5, PM ET.

So his team took completely germ npr microbes obesity mice and basically fed nnpr human gut bacteria. We're looking for those creatures that we want to give. Sucking may be one of the most beneficial ways to clean a baby's dirty pacifier, a study found iStockphoto. Could we all be Martians in origin? And it's their diets.

Bacterial Bonanza: Microbes Keep Us Alive There are 10 times more microbial cells on and in our bodies than there are human cells. While other studies have looked at putting human gut microbes into animal models before, this is the first to use DNA sequencing tools to really track changes in response to diet, says Mekalanos. The answer: Obviously, your parents' genes matter, but it turns out we humans have two sets of genes in us: the ones we inherited from our human ancestors and the ones that walk in through our mouths starting when we're just hours old. Certain bacteria have been linked to the incidence of stomach ulcers, but take away those bacteria with antibiotics, and young people get more asthma, hay fever, allergies and eczema.

He says it will take much npr microbes obesity work to learn mmicrobes changing a person's existing gut bacteria can make them lose or gain weight. Michaeleen Doucleff. So it's that population's microbes that are installed into the guts of these sterile mice. This text may not be in its final form and may be updated or revised in the future. The rest are from bacteria, viruses and other microorganisms. Yeah, all right. The obese community was transformed so that the mouse that harbored it began to acquire the features of the lean community.

ALSO READ: Factor Associated With Obesity On The Rise

Science Source hide caption. That may be because infants deliberately suppress their immune systems so that essential microbes have a chance to settle in. But Mekalanos says that this new study makes it more likely that scientists will be able to explore those possibilities "because one needs a pre-clinical model before one devises complicated, expensive human subjects trials. NPR Shop. That's especially true for children. Heard on All Things Considered.

Dreaming of slimming gut microbes? Then the team explored what would happen to these microbes if mice were switched from their standard low-fat, plant-rich mouse chow to a diet that corset fat high in fat and sugar. That was the biggest surprise for John Mekalanos, chairman of the department of microbiology and molecular genetics at Harvard Medical School, who co-wrote a commentary that appeared with the research report. It's becoming clear that these tiny companions play a much more complex and important role in human health than thought. Sick of Getting Sick? The Inuit's intestinal bacteria are great at digesting oats; the Argentinian's bacteria don't much care for oats.

Scientists have discovered new clues about obesity microbes in our digestive systems may affect health. Obesit medical solution, still experimental, was to replace her dangerous digestive bacteria with a healthier mix of microbes. The researchers found that "obese bacteria" might lead to more weight gain. We're looking for those creatures that we want to give. NPR Shop.

And the presence - the presence of - it sounds very dramatic and the results were actually quite dramatic. This text may not be in its final form and may be updated or revised in the future. Of course the mice are designed to incorporate the features npr microbes obesity the very human population that we want to help. But with new genetic probes, they can do a kind of census. The bacteria have genes that make them better at harvesting calories from food. There's been a lot of work trying to understand how these trillions of organisms relate to our health status. In an article accompanying the report, Alan Walker and Julian Parkhill of the Wellcome Trust Sanger Institute in Britain called the findings an "intriguing" step toward finding ways to fight obesity, including developing "relatively simple mixtures of bacteria for testing as anti-obesity therapeutics.

Facebook Twitter Flipboard Email. The researchers then transplanted those microbes into the guts of lab mice who didn't have any of their own microbes. When looking just at the obese people in the study, the scientists found the people with the least bacterial diversity were likelier than those with a greater variety of microbes to keep gaining weight during the nine years the researchers kept track. But that couldn't be farther from the truth," Gordon says. Now, U. NPR Shop. Ryan T.

The medical solution, still experimental, was to replace her dangerous digestive bacteria with a healthier mix npr microbes obesity microbes. September 5, PM ET. He points to an example of a patient infected with the Clostridium difficile bacteriawhich causes severe diarrhea and can frequently return, even when treated with antibiotics.

Rob Stein. We did the same thing for the jicrobes twin and waited. Childhood obesity is on the rise in many countries and overuse of antibiotics is now on the radar as a possible factor in the epidemic. There were job vacancies in the obese community, openings that were filled by these organisms from a lean gut community.

ALSO READ: Treating Obesity Hypoventilation Syndrome Pathophysiology

In addition, the data don't show that the antibiotics cause the toddlers to be heavier. The mice end up with a collection of gut microbes that mimic the obesty found in the original human sample. There's also an estimated times more microbial genes than the genes in our human genome. Though scientists don't yet understand why certain populations of microbes may be associated with obesity, Gordon says they plan to do further studies to see if targeting specific communities of microbes could change our body's relationship with digesting our food, which could then lead to new therapies to combat obesity. September 5, PM ET.

He's building obesjty microbiome. And I think you're alluding to the fact that obesity is a very complex puzzle with lots of parts - how much food we consume, how much exercise we do each day. We knew who the actors were, but we also asked the question, why isn't there an epidemic of leanness if these things can occur, at least in this setting. Louis School of Medicine. The researchers also followed a group of 19 Karen refugees as they relocated from Thailand to America, tracking how their gut microbiomes changed during the transition. Bacterial Bonanza: Microbes Keep Us Alive There are 10 times more microbial cells on and in our bodies than there are human cells. The medical solution, still experimental, was to replace her dangerous digestive bacteria with a healthier mix of microbes.

The research could lead to new ways to prevent heart disease by shifting the mix npr microbes obesity gut bacteria. Researchers say the harmless bacteria in parents' saliva works by stimulating the babies' immune system. September 15, PM ET. Louis, and his colleagues removed bacteria from the guts of four pairs of human twins in which one was obese and the other was lean. Embrace Your Inner Bacteria! Accessibility links Skip to main content Keyboard shortcuts for audio player. Bacterial Bonanza: Microbes Keep Us Alive There are 10 times more microbial cells on and in our bodies than there are human cells.

Obesity on Science Friday. If a person has a physiological state -- if they're npt or if they have diseases like inflammatory bowel disease -- how much of that disease is attributable to their microbial communities, and how can we establish that relationship? Accessibility links Skip to main content Keyboard shortcuts for audio player. But exactly how these drugs fatten up cattle, pigs and chickens is a bit mysterious.

He and other scientists are eager to start doing experiments to see what happens if the gut populations are modified npr microbes obesity changes in diet, antibiotics, or dietary supplements. Louis hide caption. That will allow researchers "to be able to look at this intimate relationship between our microbial selves and our human cellular selves," Gordon says. November 12, PM ET. The answer: Obviously, your parents' genes matter, but it turns out we humans have two sets of genes in us: the ones we inherited from our human ancestors and the ones that walk in through our mouths starting when we're just hours old. But the Food and Drug Administration worried that the still-experimental procedure put patients at risk. No one currently knows if gut bugs are an important contributor to human obesity or if targeting them could lead to novel therapies.

Facebook Twitter Flipboard Email. But when Gordon exposed the mice to "this big, bad, dirty microbws as Gibson calls it, the obesity suddenly turned their food into more calories and gained weight. Your Health. And, finally, the researchers showed that the animals were unable to be colonized by the lean microbes when they were fed diets aimed at simulating a typical unhealthful Western diet high in saturated fats and low in fiber. After 10 days, the researchers found that the mice with the obese microbes adopted the lean microbes and started to look healthier. A high-fat, high-sugar diet can quickly and dramatically change the population of microbes living in the digestive tract, according to a new study of human gut bugs transplanted into mice. Louis School of Medicine.

By using twins, the researchers were trying to eliminate any genetic variation that could influence the results. But the Food and Drug Administration worried that the still-experimental procedure put patients at risk. The work is npr microbes obesity the beginning of what Gordon hopes will be a whole slew of experiments to tease out how diet and microbes interact to affect nutrition and weight gain. In addition, the data don't show that the antibiotics cause the toddlers to be heavier. Using powerful DNA sequencing tools that allow them to take a "census" of the gut bugs without having to culture them, Gordon's team then showed that this kind of microbe transplant is successful. By more diversity, he means that the leaner folks had more intestinal bacteria — 40 percent more — and many more species of bacteria than the people who were fatter. The medical solution, still experimental, was to replace her dangerous digestive bacteria with a healthier mix of microbes.

So Ehrlich and his colleagues conducted a detailed analysis of the microbes in the guts of nearly Danish people. The rest are from bacteria, viruses and other microorganisms. Who lives here in the large intestine? Shots - Health News.

Heard on All Things Considered. Recent studies have suggested that certain populations of microbes may be associated with obesity. Facebook Twitter Flipboard Email. Microbiologist Ronald Evans of the Salk Institute in California, who wrote an article accompanying the studies, agrees. Now, U.

  • The researchers then transplanted those microbes into the guts of lab mice who didn't have any of their own microbes.

  • The mice were skinny because they had no bacteria in their intestines. Rob Stein.

  • Food For Thought.

  • Accessibility links Skip to main content Keyboard shortcuts for audio player.

  • Babies given antibiotics within the first 6 months of life were more likely to be overweight as toddlers than babies not exposed to the drugs, though the study couldn't prove antibiotics were the cause.

  • It's a very complex relationship. They simply demonstrate a correlation.

The mice first ate a pnr low-fat, plant-rich mouse chow. From birth to death, they shape our health — and not always for the worse. September 15, PM ET. He says this study shows the way ahead, because it used DNA sequencing techniques to identify interesting changes in gut microbes. Accuracy and availability may vary. The lean bugs went into the obese community, transforming it, but not vice versa.

Maanvi Singh. Part of Gordon's research involves looking at the populations of microbes that may be associated obesity obesity. Perhaps even more surprising and important: People who had less microbial diversity — whatever their weight — were more likely to have a variety of risk factors for Type 2 diabetes, heart disease and cancer. Dreaming of slimming gut microbes? Among that group of 19 refugees, researchers noticed that a Western bacteria strain called Bacteroides began to displace the non-Western strain Prevotella within their first six to nine months in the U. Jeffrey Gordon explains how they contribute to the physiology of the human body and why they may hold the key to fighting some diseases.

Having too few species, regardless of your weight, appears to increase the risk for Microbee 2 diabetes, heart disease and cancer. Evidence has been mounting in recent years that bacteria and other organisms in our bodies do a lot more than just help us digest food. Nearly 30 percent of the infants were given antibiotics within the first 6 months of life, and these children tended to be overweight or obese as toddlers when compared to babies not exposed to the drugs.

  • That's what we call the battle of the micro biota. The issue, then was to determine which came first: the fat, or the bacteria.

  • The findings, though preliminary, suggest a future path for obesity treatment.

  • All rights reserved.

Npr microbes obesity lean bugs went into the obese community, transforming it, but not vice versa. Next, Ley looked at twelve obese people. September 15, PM ET. Ryan T. Jeffrey Gordon explains how they contribute to the physiology of the human body and why they may hold the key to fighting some diseases. A new study of first- and second-generation Hmong and Karen immigrants finds their gut microbiomes changed soon after moving to the U. It turned out that the obese mice had a smaller proportion of a kind of bacteria known as Bacteroidetes.

  • So it's evident to us that these job vacancies can't be fulfilled unless the right diet is being consumed.

  • The researchers also identified eight species of bacteria that appeared to be missing among the people whose microbes were depleted, raising the possibility of someday creating a probiotic that could help.

  • That's step one. Second-generation Hmong- and Karen-Americans — born in the U.

  • The Inuit's intestinal bacteria are great npr microbes obesity digesting oats; the Argentinian's bacteria don't much care for oats. After 10 days, the researchers found that the mice with the obese microbes adopted the lean microbes and started to look healthier.

  • For one, "I think my parents realized they don't have to go out and kill one every time we want to eat chicken," Vang says.

  • Food For Thought.

A high-fat, high-sugar diet can quickly and dramatically change the population of microbes living in the microges tract, according to a new study of human gut bugs transplanted into mice. They simply demonstrate a correlation. Louis, and his colleagues removed bacteria from the guts of four pairs of human twins in which one was obese and the other was lean. Subscribe to Health Newsletter. Another report, published Tuesday in the International Journal of Obesitysuggests that these findings may have implications for people, too. Facebook Twitter Flipboard Email.

Second-generation Oobesity and Karen-Americans — born in the U. They simply demonstrate a correlation. Some of the strains they lose are ones that help them break down and glean nutrients from fibers found in Southeast Asian staples like wild greens, coconut and tamarind. Accessibility links Skip to main content Keyboard shortcuts for audio player.

In a companion study, pediatricians from NYU looked at how antibiotics may have influenced the mirobes of 11, babies born in the U. And your bacteria community, well, it's different than mine; everyone has a different community and that is important because as a new study published in Science points out, the specific bacteria you shelter can alter your metabolism. If a person has a physiological state -- if they're obese or if they have diseases like inflammatory bowel disease -- how much of that disease is attributable to their microbial communities, and how can we establish that relationship? And of course, what kind of foods should we create to help cultivate this microbial garden? GORDON: Well, it would be useful to look at the lifestyles of lean individuals, but at the same time, yes, it's not easy, but there is hope.

Having too few species, regardless of your weight, appears to increase the risk for Type 2 diabetes, heart disease and cancer. Accessibility links Skip to main content Keyboard shortcuts for audio player. Researchers say the harmless bacteria in parents' saliva works by stimulating the babies' immune system. Accessibility links Skip to main content Keyboard shortcuts for audio player. But the Food and Drug Administration worried that the still-experimental procedure put patients at risk. Now a new study suggests that a high-fat, high-sugar diet can produce big changes in those microbes and the changes might actually contribute to obesity.

And I think that these types of experiments point to another facet of our biology that we might be able to manipulate intentionally in ways that could enforce health and perhaps at very early stages of our lives. We're looking for those creatures that we want to give. European researchers found that the less diverse those microbes are, the more likely people are to gain weight, become obese and develop risk factors for serious health problems. In addition, the data don't show that the antibiotics cause the toddlers to be heavier. And of course, what kind of foods should we create to help cultivate this microbial garden? So we're really a compendium [and] an amalgamation of human and microbial parts. Heard on Morning Edition.

It's becoming clear that these tiny companions play a much more complex corset fat redistribution after weight important role in human health than thought. And that finding could shed light on what happens in humans. That's especially true for children. NPR Shop. Science Source hide caption.

Nicrobes is internationally known for his research on gut microbial communities and gastrointestinal development. The patient was treated with a transfusion of gut microbials from a healthy individual's fecal material to restore the bacterial flora in the intestinal tract -- and symptoms improved. NPR Shop. They simply demonstrate a correlation. Plus, if antibiotics are contributing to the obesity epidemic, it's one factor that doctors can control.

A study, npr microbes obesity online today in npf journal Naturefinds that antibiotics make young mice fatter by changing the mix of their gut bacteria. The evidence just keeps mounting that the microbes in our digestive systems are a factor in the obesity epidemic. The elevated risk decreased when the children reached 7 years of age, and exposure to antibiotics later in life didn't have a significant impact on weight. Not surprisingly, a person who grows up in Argentina and another who grows up in northern Alaska tend to acquire different bacteria in their intestines and mouths -- and, stunningly, these differences seem to matter. Imagine a Cheerio sliding down the digestive tracts of an Inuit and an Argentine.

Heard on All Things Considered. Bad bug: The bacterium Clostridium difficile kills 14, people in the United Npr microbes obesity each year. Now it is dropping plans to restrict transplants after doctors and patients complained. September 5, PM ET. The human body is home to trillions of bacteria. He is internationally known for his research on gut microbial communities and gastrointestinal development.

By probiotic you're referring to a different type of probiotic, not the type of probiotics that are present in fermented milk products that everybody is obeeity familiar with. That will allow researchers "to be able to look at this intimate relationship between our microbial selves and our human cellular selves," Gordon says. For one, "I think my parents realized they don't have to go out and kill one every time we want to eat chicken," Vang says. And yes, we have to figure out which one of these groups of bacteria are most helpful in different populations of people. It's busy down there: a gut bacterium splits into two, becoming two new cells.

An immune suppression system in the blood of newborn babies could be key to building a healthy microbiome. In an article accompanying the report, Alan Walker and Julian Parkhill of the Wellcome Trust Sanger Institute in Britain called the findings an "intriguing" step toward finding ways to fight obesity, including developing "relatively simple mixtures of bacteria for testing as anti-obesity therapeutics. Facebook Twitter Flipboard Email. If a person has a physiological state -- if they're obese or if they have diseases like inflammatory bowel disease -- how much of that disease is attributable to their microbial communities, and how can we establish that relationship?

ALSO READ: Obsessive Internet Use Linked Depression

Visit our website terms of use and permissions pages at www. Obeaity too few species, regardless obesity your weight, appears to increase the risk for Type 2 diabetes, heart disease and cancer. Since the s, farmers have known that small amounts of antibiotics increase the weight of livestock by as much as 15 percent. And I think you're alluding to the fact that obesity is a very complex puzzle with lots of parts - how much food we consume, how much exercise we do each day. Obesity Latest U. And here we have evidence for cause, and that's helpful.

Accuracy and availability may obwsity. The source: obese and lean human twins. Heard on All Things Considered. He says this study shows the way ahead, because it used DNA sequencing techniques to identify interesting changes in gut microbes. November 1, PM ET. Recent studies have suggested that certain populations of microbes may be associated with obesity. And in some cases, they hadn't really changed too much about their diet.

And when this new collection of human microbes was transplanted into germ-free obesoty, the mice gained an increased amount of fat tissue even when fed low-fat diets, compared to mice that got human microbes from mice fed low-fat diets. Louis hide caption. Nevertheless, the results are provocative. The Inuit gains weight.

Accessibility links Skip to main content Keyboard shortcuts for audio player. They npg demonstrate a correlation. All npr microbes obesity supports the ideas that eating a poor diet or taking lots of antibiotics may be factors in the obesity epidemic and associated health problems, in part, because of the way they affect our gut microbes, Ehrlich says. He's not just getting a cold.

A study, published online today in the journal Naturefinds that antibiotics make young mice fatter npr microbes obesity changing the mix of obesiyt gut bacteria. We may not see them, but we need them. Nearly 30 percent of the infants were given antibiotics within the first 6 months of life, and these children tended to be overweight or obese as toddlers when compared to babies not exposed to the drugs. A high-fat, high-sugar diet can quickly and dramatically change the population of microbes living in the digestive tract, according to a new study of human gut bugs transplanted into mice. An immune suppression system in the blood of newborn babies could be key to building a healthy microbiome.

Shots - Health News. Others prefer the desert-dry skin of the forearm. Billie Iverson, 86, of Cranston, R. Accessibility links Skip to main content Keyboard shortcuts for audio player. A study, published online today in the journal Naturefinds that antibiotics make young mice fatter by changing the mix of their gut bacteria.

So we tried to make the battle more realistic. Visit our website terms of use and permissions pages at www. Louis hide caption. NPR Shop.

  • The first battle of the micro biota was done with mice eating a standard mouse chow.

  • Subscribe to Health Newsletter.

  • The other half got bacteria from fat mice.

  • NPR Shop.

Gordon's research shows that these microbes living in our bodies aren't just there for the ride -- they're actively contributing to the normal npr microbes of the human body. Accuracy and availability may vary. Well, thank you very much, Dr. The research also showed that people with less diverse communities of gut microbes were more likely to be at risk for health problems associated with being overweight, including diabetes, heart disease and cancer. Facebook Twitter Flipboard Email.

Now, U. You looked at gut bacteria and how it could transmit lean or obese traits. September 15, PM ET. November 12, PM ET.

One npr microbes obesity said parents would be better off spending their money micdobes good food for their kids instead of probiotics. It remains unknown how much of a difference microbes might make to obesity and fat levels when compared to, say, exercise. He's building his microbiome. There were job vacancies in the obese community, openings that were filled by these organisms from a lean gut community.

Trend Sweeping the Globe Sept. The question was, could our microbial communities, which are tasked with the responsibility of transforming the foods that we eat into npr microbes obesity products that shape our biology and our biological differences, what role do they play? So his team took completely germ free mice and basically fed them human gut bacteria. Among that group of 19 refugees, researchers noticed that a Western bacteria strain called Bacteroides began to displace the non-Western strain Prevotella within their first six to nine months in the U. Louis School of Medicine, who studies the microbes that live on and in us, offers this factoid: "We think that there are 10 times more microbial cells on and in our bodies than there are human cells. Accuracy and availability may vary.

ALSO READ: Childhood Obesity Vine

Facebook Twitter Flipboard Email. Facebook Twitter Flipboard Email. Evidence has microbss mounting in recent obesity that bacteria and other organisms in our bodies do a lot more than just help us digest food. This text may not be in its final form and may be updated or revised in the future. Facebook Twitter Flipboard Email.

  • Npe when you reach for a cookie, keep in mind that you're not the only one who will enjoy the treat: It will also get eaten by the bacteria living in your gut. Some of the bacteria in our guts feed, and survive, on particular fibers found in grains and greens — and die off when they don't get enough.

  • So we're really a compendium [and] an amalgamation of human and microbial parts.

  • That transformation prevented the development of increased body weight and fat content and eliminated the metabolic features associated with obesity. Now, U.

  • Since the s, farmers have known that small amounts of antibiotics increase the weight of livestock by as much as 15 percent.

  • Scientists have discovered new clues about how microbes in our digestive systems may affect health.

Obesity Latest U. So we did a test. Visit our website terms of use and permissions pages at www. Rob Stein.

Perhaps even more surprising and important: People who had less microbial diversity — whatever their weight — were more likely to obwsity a variety of risk factors for Type 2 diabetes, heart obesity and cancer. Also, special thanks to the "bacteria" recruited for the radio skit: NPR's Margot Adler, Jim Zarroli, Agnes Janiszewski and -- especially because of his extraordinary ability to scream with delight -- Josh Rogosin. If a person has a physiological state -- if they're obese or if they have diseases like inflammatory bowel disease -- how much of that disease is attributable to their microbial communities, and how can we establish that relationship? NPR Shop. Enlarge this image.

Obesity did the same thing for the lean twin and waited. That's step one. Both groups put on body fat. So we did a test. Mcirobes scientists don't yet understand why certain populations of microbes may be associated with obesity, Gordon says they plan to do further studies to see if targeting specific communities of microbes could change our body's relationship with digesting our food, which could then lead to new therapies to combat obesity.

There's growing evidence that the bacteria jpr our gut influence our healthincluding how much we weigh. The bacteria switched on genes involved in fat metabolism. Tell us how you tested that. But the mice that received bacteria from obese donors gained more fat over the course of the experiment.

ALSO READ: Antipsychotic Weight Gain Chart For Obese

First of all, the remarkable things was that the invasion was one way. Getting the Goods on 'Good Bacteria' July 19, Further research could also reveal what immigrants — and all Americans — who are struggling with obesity can do to improve their health. Leonardo Trasandethe lead pediatrician on the study, tells Shots, "we predict that that this rise in body mass would increase the overweight population in the U. Nell Greenfieldboyce. Rob Stein.

That's especially true for children. Heard on Morning Edition. Next, the scientists let the animals live together. Obesity, that raises the question: Can I change what I've got? But exactly how these drugs fatten up cattle, pigs and chickens is a bit mysterious. All over the world, teams of scientists are looking at how bacteria affect the folks they live in.

And that finding could shed light on what happens in humans. Sucking may be one of the most obesity ways to clean a baby's dirty pacifier, a study found iStockphoto. He points to an example of a patient infected with the Clostridium difficile bacteriawhich causes severe diarrhea and can frequently return, even when treated with antibiotics. Plus, if antibiotics are contributing to the obesity epidemic, it's one factor that doctors can control.

The other half got bacteria from fat mice. August 28, PM ET. Perhaps even more surprising and important: People who had less microbial npr microbes obesity — whatever their weight — were more likely to have a variety of risk factors for Type 2 diabetes, heart disease and cancer. That may be because infants deliberately suppress their immune systems so that essential microbes have a chance to settle in. Accessibility links Skip to main content Keyboard shortcuts for audio player.

Facebook Twitter Flipboard Email. Using powerful ,icrobes sequencing tools that allow them to take a "census" of the gut bugs without having to culture them, Gordon's team then showed that this kind of microbe transplant is successful. And here you have an example of a transplantation of a microbial community The Inuit gains weight. September 15, PM ET. These genes aren't from your parents, but the genetic code of the bacteria in your gut can determine your health -- and affect conditions like type 1 diabetes and obesity.

Could we all be Martians in origin? Bad bug: The bacterium Clostridium difficile kills 14, people in the United States each year. Accuracy and availability may vary. Half of them got bacteria taken from skinny mice. You ibesity at gut bacteria and how it could transmit lean or obese traits. Leonardo Trasandethe lead pediatrician on the study, tells Shots, "we predict that that this rise in body mass would increase the overweight population in the U. The question was, could our microbial communities, which are tasked with the responsibility of transforming the foods that we eat into metabolic products that shape our biology and our biological differences, what role do they play?

It surprised John Mekalanos. NPR Shop. The mice first ate a healthy low-fat, plant-rich mouse chow. You know, the research in the news that's coming out as if we discovered something new.

Bacterial Bonanza: Microbes Keep Us Alive There are 10 times more microbial cells on and in our bodies than there are human cells. If a person has a physiological state -- if they're obese or if they have diseases like inflammatory bowel disease -- how much of that disease is attributable to their microbial communities, and how can we establish that relationship? But changes in diet didn't explain all — or even most — of the change in immigrants' microbiomes. Are there vital functions that aren't represented in the microbiota of an obese individual. One researcher said parents would be better off spending their money on good food for their kids instead of probiotics. The medical solution, still experimental, was to replace her dangerous digestive bacteria with a healthier mix of microbes.

The lean bugs went into the obese community, transforming it, but not vice versa. There were job vacancies in obesiry obese community, openings that were filled by these npr microbes obesity from a lean gut community. This text may not be in its final form and may be updated or revised in the future. What connection do they have to our well-being? Your Health. Part of Gordon's research involves looking at the populations of microbes that may be associated with obesity. First of all, the remarkable things was that the invasion was one way.

FLATOW: So it's not as easy as hanging out with leaner people and you might get some of their bacteria that you might like to make you lean? Npr microbes obesity any case, Vangay notes, researchers are still untangling the influence of diet and microbiome on obesity. Until a couple of years ago, scientists didn't have the tools to figure out exactly what lives in a person's digestive tract. A lot changed for Minnesota-based chef Yia Vang's family when they fled persecution in Laos and, inresettled in the American Midwest. Another report, published Tuesday in the International Journal of Obesitysuggests that these findings may have implications for people, too.

These genes aren't from your parents, but the genetic code of the bacteria in your gut can determine your npr microbes obesity -- and affect conditions like type 1 diabetes and obesity. Robert Krulwich. Evidence has been mounting in recent years that bacteria and other organisms in our bodies do a lot more than just help us digest food. Here month-old twins are weighed in a nutritionist's office in Colombia. They found that in less than 24 hours the gut's microbial populations changed abruptly, according to a study in the journal Science Translational Medicine. The Argentine makes more frequent visits to the restroom. Gordon's research shows that these microbes living in our bodies aren't just there for the ride -- they're actively contributing to the normal physiology of the human body.

Npr microbes obesity are ingredients in the diet that the bacteria can utilize, can process in ways that help themselves as well as help us, and the diet and microbes collude, collaborate, the shape, the properties obbesity these communities, and affect us. Enlarge this image. If a person has a physiological state -- if they're obese or if they have diseases like inflammatory bowel disease -- how much of that disease is attributable to their microbial communities, and how can we establish that relationship? I think that the ability to describe differences between microbial communities and healthy and diseased populations is one important step. The result was mice with microbe communities in their guts that mimic the ones found in people. So his team took completely germ free mice and basically fed them human gut bacteria.

Since it's controlling metabolism, what about other things that are going on npr microbes obesity the body? The mice end up with a collection of gut microbes that mimic the populations found in the original human sample. Visit our website terms of use and permissions pages at www. And I think that these types of experiments point to another facet of our biology that we might be able to manipulate intentionally in ways that could enforce health and perhaps at very early stages of our lives.

Heard on Fresh Air. Among that group of 19 refugees, researchers noticed that a Western bacteria strain called Mivrobes began to displace the non-Western strain Prevotella within their first six to nine months in the U. He's building his microbiome. And I think you're alluding to the fact that obesity is a very complex puzzle with lots of parts - how much food we consume, how much exercise we do each day.

Research on that is only just beginning. The findings, though preliminary, mcrobes a future path for obesity treatment. It's busy down there: a gut bacterium splits into two, becoming two new cells. Conaty for NPR hide caption. What do they do? The human body is home to trillions of bacteria. Others prefer the desert-dry skin of the forearm.

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